C#

using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Text;
using System.Windows.Forms;

namespace Flickering
{
    public partial class Form1 : Form
    {
        public Form1()
        {
            InitializeComponent();

            this.SetStyle( 
                ControlStyles.UserPaint | 
                ControlStyles.AllPaintingInWmPaint |
                ControlStyles.OptimizedDoubleBuffer, true);
            this.UpdateStyles();

            CreatePictureBoxes();
        }

        private void CreatePictureBoxes()
        {
            Random rand = new Random();

            for (int i = 0; i < 150; i++)
            {
                PictureBox pictureBox = new PictureBox();
                pictureBox.BackColor = Color.Red;
                pictureBox.BorderStyle = System.Windows.Forms.BorderStyle.FixedSingle;
                pictureBox.Location = new Point(rand.Next(200), rand.Next(200));
                pictureBox.Name = "pictureBox" + i;
                pictureBox.Size = new System.Drawing.Size(20,20);
                pictureBox.TabIndex = 0;
                pictureBox.TabStop = false;

                this.Controls.Add(pictureBox);
            }
        }

        private void button1_Click(object sender, EventArgs e)
        {
            Random rand = new Random();

            for (int i = 0; i < 150; i++)
            {
                if (Controls[i] != (Control)button1)
                {
                    this.Controls[i].Location = new Point(rand.Next(200), rand.Next(200));
                    //if( i % 10 == 0 ) this.Update();
                }
            }
        }
    }
}

namespace Flickering
{
    partial class Form1
    {
        /// <summary>
        /// Required designer variable.
        /// </summary>
        private System.ComponentModel.IContainer components = null;

        /// <summary>
        /// Clean up any resources being used.
        /// </summary>
        protected override void Dispose(bool disposing)
        {
            if (disposing && (components != null))
            {
                components.Dispose();
            }
            base.Dispose(disposing);
        }

        #region Windows Form Designer generated code

        /// <summary>
        /// Required method for Designer support - do not modify
        /// the contents of this method with the code editor.
        /// </summary>
        private void InitializeComponent()
        {
            this.button1 = new System.Windows.Forms.Button();
            this.SuspendLayout();
            // 
            // button1
            // 
            this.button1.Location = new System.Drawing.Point(207, 234);
            this.button1.Name = "button1";
            this.button1.Size = new System.Drawing.Size(71, 26);
            this.button1.TabIndex = 0;
            this.button1.Text = "button1";
            this.button1.UseVisualStyleBackColor = true;
            this.button1.Click += new System.EventHandler(this.button1_Click);
            // 
            // Form1
            // 
            this.AutoScaleDimensions = new System.Drawing.SizeF(6F, 13F);
            this.AutoScaleMode = System.Windows.Forms.AutoScaleMode.Font;
            this.ClientSize = new System.Drawing.Size(284, 264);
            this.Controls.Add(this.button1);
            this.Name = "Form1";
            this.Text = "Form1";
            this.ResumeLayout(false);

        }

        #endregion

        private System.Windows.Forms.Button button1;
    }
}