Hello ,
First use DatGridview.CellClick Event that already described by DamithSL and then check the ColumnIndex of the clicked cell by this way .
var columnindex= dataGridView.CurrentCell.ColumnIndex;
var nextcolumnindex=columnindex+1 ;
var nextcolumnvalue =dataGridView.Rows[e.RowIndex].Cells[nextcolumnindex].Value;
thanks