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If you want to quickly get index suggestions and improve performance in SQL Server, then Profiler and tuning wizard is the first place to start.
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How to solve performance issues in data migration to SQL Server.
by ASP.NET Community
Some optimizations can be done directly to IIS and you will reap improvements farther down the line.Planning, testing and tuning for ASP.NET and
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About how to get high performance from your website and get a good score from Yslow