how to handle show a meesage when users close from browser

you can use following script as 

var confirmOnPageExit = function (e) {
     // If we haven't been passed the event get the window.event
     e = e || window.event;

     var message = 'Your information will be lost. Are you sure ?';

     // For IE6-8 and Firefox prior to version 4
     if (e) {
         e.returnValue = message;
     }

     // For Chrome, Safari, IE8+ and Opera 12+
     return message;
 };


 // Turn it on - assign the function that returns the string
 window.onbeforeunload = confirmOnPageExit;

DeActivate on Submit button

<input type="submit" onclick="window.onbeforeunload = null; " value="Save"  />

For the new changes in input fields

$('input').blur(function () {

      window.onbeforeunload = confirmOnPageExit;
  });